Products & ReviewLife Sciences
(+)-Bay K8644
L-type calcium channel inhibitor
(+)-Bay K8644
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(+)-Bay K8644, a modulator of potential operated calcium channels, exists as two enantiomers that have opposite actions (Hess et al.; Nowycky et al.; O'Neill et al.; Ravens et al.; Yamamoto et al.). (+)-Bay K8644 is an L-type channel blocker that has negative inotropic and vasodilatory effects (Artigas et al.; Franckowiak et al.; Ravens et al.).
REPROGRAMMING
- When combined with BIX-01294, enables reprogramming of mouse embryonic fibroblasts after transduction with OCT4 and KLF4 only (Shi et al.).
DIFFERENTIATION
- Increases neuronal differentiation from neural stem and progenitor cells (NSCs) derived from the brains of postnatal mice (D'Ascenzo et al.).
