BIOne Single-Use Bioreactor System
The BIOne benchtop scale single-use bioreactor (SUB) is for mammalian cell growth, cell therapy, insect cells, and other unique applications performed in a stirred tank bioreactor. The gamma irradiated BIOne SUB is engineered with a disposable headplate welded to a triple-layered liner that can be easily inserted into a non-sterile bioreactor glass vessel, converting it to a disposable SUB within a matter of seconds.
The supplier does not provide quotations for this product through SelectScience. You can search for similar products in our Product Directory.
The BIOne benchtop scale single-use bioreactor (SUB) is for mammalian cell growth, cell therapy, insect cells, and other unique applications performed in a stirred tank bioreactor. The gamma irradiated BIOne SUB is engineered with a disposable headplate welded to a triple-layered liner that can be easily inserted into a non-sterile bioreactor glass vessel, converting it to a disposable SUB within a matter of seconds. Upon media addition, the liner expands and molds to the glass vessel, preserving the geometry of the existing bioreactor.
The BIOne SUB’s liner material emulates the large-scale SUBs used in pilot and commercial biopharma production facilities around the world. Performing R & D studies using the most similar material on the market streamlines your tech transfer and can de-risk your process BEFORE transferring to pilot scale.
CUSTOMIZABLE ABOVE & BELOW THE HEADPLATE
- 2L & 5L Working Volume
- Optional Single-Use pH Probe
- Increased Throughput
- Weldable Tubing
- Flute, Micro & Open Pipe Sparging Options
- Non-Invasive DO & Optional pH Probe Ports
- USP Class VI Materials
- Repligen® ATF Perfusion Tube Compatible
- Animal Derivative-Free
- Low Antioxidant Liner Material
- Compatible with Most Manufacturers’ Glass Vessels and Controllers
DO & pH PROBE PORTS
- Non-Invasive (Amperometric DO/Optical pH)
- PG-13.5 (Optical DO/Electrochemical pH)
- Optional Integrated Single-Use pH Probe
PITCHED BLADE IMPELLER
- Single or Dual Impeller
SPARGING OPTIONS
- Flute Sparger (7 x 1.5 mm hole)
- Micro Sparger (20-40 μm pore size)
- Open Pipe Sparger (1 x 3.0 mm)
LOW ANTIOXIDANT LINER MATERIAL
- Outer Layer (LDPE) – Mechanical Strength
- Middle Barrier Layer (EVOH) – Gas Barrier
- Contact Layer (ULDPE) – Cell Culture Compatible, Biologically Inert
