CardioExcyte 96
The CardioExcyte 96 is a 96 well plate-based hybrid device supporting highly resolved impedance-based measurements and electric field potential recordings. It analyses the contractility and electrophysiology of cellular cardiac networks, as well as morphological changes, e.g. cytotoxic responses, of non-contractile cells such as hepatocytes, cancer cells, cell lines or stem cells.
Detecting drug effects on cardiomyocyte function in vitro
An easy to use device and the support that we get from Nanion e.g. when it comes to any new assay development is superb. They are always available upon a quick email or call. I really like to work with the Nanion team.
Review Date: 28 Feb 2022 | Nanion Technologies GmbH
Toxicity studies
Measuring the toxicity of selected model compounds was straightforward and reliable. A great option to expand your field of vision, particularly during long-term toxicity studies.
Review Date: 1 Jul 2020 | Nanion Technologies GmbH
Detecting drug effects on cardiomyocyte function in vitro
We have being using CardioExcyte since 2017 and are happy with the instrument and the high quality data it generates.
Review Date: 28 May 2020 | Nanion Technologies GmbH
With embedded electronics and a sophisticated sensor technology integrated in the well-plate based consumables, the CardioExcyte 96 is a turn-key system for efficient impedance and extracellular field potential measurements. The CardioExcyte 96 package includes an Incubation System which makes the system independent of an incubator. The system is placed on the bench top with maintained control over temperature, gas mix and humidity.
Efficiency and ease-of-use are facilitated by an outstanding software package for data handling and export - an essential part of the CardioExcyte 96 system. The system has been validated with stem cell-derived cardiomyocytes from all major stem cell providers, as monolayers or beating 3D-clusters, as well as with cell lines (hepatocyte-like cells, cancer cells etc.) for cytotoxicity studies.
Impedance and extracellular field potential measurements are performed at high resolution, are non-invasive and label-free.
Features:
- Impedance & extracellular field potentials from the same well 96 recording wells in parallel
- Non-invasive & label-free measurements
- High resolution
- Electrical and optical pacing options
- Acute and chronic assessment of cell activity and toxicity
- Part of the CiPA validation study
- Long-term studies of several days possible