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CAY10585

Name: CAY10585
SKU: 72432
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STEMCELL Technologies Inc.72432

Hypoxia inducible factor-1a (HIF1a) inhibitor

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CAY10585

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CAY10585 inhibits hypoxia inducible factor 1 (HIF-1) accumulation in a concentration and time-dependent manner and significantly suppresses transcriptional activity of HIF-1 target genes (Lee et al.).

DIFFERENTIATION

Inhibits BMP9- and HIF-1-induced osteogenic differentiation in mesenchymal stem cells (Hu et al.).
Rescues cardiomyocyte differentiation in Fgfr1(-/-) mouse embryonic stem cells (Crescini et al.).