ChemiSCREEN™ Human Recombinant mGlu2 Metabotropic Glutamate Receptor Calcium-Optimized Stable Cell Line
EMD Millipore’s cloned human mGlu2-expressing cell line is made in the Chem-1 host, which supports high levels of recombinant mGlu2 expression on the cell surface and contains high levels of the promiscuous G protein Gα15 to couple the receptor to the calcium signaling pathway. Thus, the cell line is an ideal tool for screening for agonists, antagonists and allosteric modulators of mGlu2.
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EMD Millipore’s cloned human mGlu2-expressing cell line is made in the Chem-1 host, which supports high levels of recombinant mGlu2 expression on the cell surface and contains high levels of the promiscuous G protein Gα15 to couple the receptor to the calcium signaling pathway. Thus, the cell line is an ideal tool for screening for agonists, antagonists and allosteric modulators of mGlu2.
