ChemiSCREEN™ Membrane Preparation Recombinant Human LPA1 Lysophospholipid Receptor
EMD Millipore's LPA1 Membrane Preparation is a crude membrane preparation made from the proprietary stable recombinant cell line that is also used for EMD Millipore’s LPA1 Calcium Optimized Cell Line (HTS089C). This LPA1 Membrane Preparation exhibits both constitutive and agonist-induced activity in GTPγS binding assays; thus it is an ideal HTS tool for screening of compounds for agonist, inverse agonist, and antagonist activi…
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EMD Millipore's LPA1 Membrane Preparation is a crude membrane preparation made from the proprietary stable recombinant cell line that is also used for EMD Millipore’s LPA1 Calcium Optimized Cell Line (HTS089C). This LPA1 Membrane Preparation exhibits both constitutive and agonist-induced activity in GTPγS binding assays; thus it is an ideal HTS tool for screening of compounds for agonist, inverse agonist, and antagonist activities. The membrane preparations exhibits EC50 of 73 nM for LPA in a GTPγS binding assay.
