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Chromolith® High Resolution HPLC Columns

Chromolith® HighResolution: High resolution separations without ultra high pressure. The revolutionary monolithic Chromolith® HighResolution columns are made from a single rod of high-purity monolithic silica, rather than from particles. Their unique bimodal pore structure allows the chromatographic performance to be improved significantly. Speed of analysis (separations up to 9 times faster if required) Separations two…

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Merck KGaA, Darmstadt, Germany

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Average Rating 4.5

|14Scientists have reviewed this product

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Great results

 

Average Rating 5.0

Application Area:

Analyze metabolites in urine sample

We achieve high-quality and highly reproducible results by using this column.

Review Date: 3 Oct 2022 | Merck KGaA, Darmstadt, Germany

Good quality-price ratio

 

Average Rating 4.0

Application Area:

Analyze small molecules

Very easy to use and good price-quality ratio.

Review Date: 29 Mar 2022 | Merck KGaA, Darmstadt, Germany

Great product to have in your tool box

 

Average Rating 4.7

Application Area:

analysis of small molecules in biological samples

Chromolith monolithic column offers very unique selectivity. It resolved a critical pair cleanly in our application. The low back pressure allowed us to use very fast flow rate and short gradient, which allowed nearly real-time monitoring of fast reactions. The column is reasonably durable, and handled simple acetonitrile-precipitated plasma samples well. Only slight efficiency reduction was observed (broader peaks) after almost 100 injections.

Review Date: 30 Jun 2017 | Merck KGaA, Darmstadt, Germany

It’s a wonderful experience to use this column

 

Average Rating 5.0

Application Area:

Low molecular binding peptide determination in plant extract

It’s a wonderful experience to use this column to check low molecular binding peptides in radionuclide (uranium) treated plant samples.

Review Date: 16 Oct 2015 | Merck KGaA, Darmstadt, Germany

Average Rating 4.7

Application Area:

Excellent HPLC

Good separation, resolution, fast, reliable and accurate.

Review Date: 2 Jan 2014 | Merck KGaA, Darmstadt, Germany

Average Rating 4.0

Application Area:

Cosmetics

Excellent, easy to use, fast analysis. We love it!

Review Date: 6 Nov 2013 | Merck KGaA, Darmstadt, Germany

Average Rating 3.0

Application Area:

amino acids quantification

It is a good column for fast and good efficiency determinations.

Review Date: 27 Aug 2013 | Merck KGaA, Darmstadt, Germany

Average Rating 4.0

Easy to use with sharp peek resolution.

Review Date: 17 Feb 2012 | Merck KGaA, Darmstadt, Germany

Average Rating 5.0

Application Area:

food analysis

One of our best performance columns in our laboratory. Good separation, long life and reproducible results.

Review Date: 17 Feb 2012 | Merck KGaA, Darmstadt, Germany

Average Rating 5.0

Application Area:

chromatography

This column was introduced at a time when analytical labs were trying to achieve UPLC type capability without having to purchase an UPLC. Excellent reproducibility, robust and a great column for a variety of applications.

Review Date: 16 Feb 2012 | Merck KGaA, Darmstadt, Germany

Chromolith® HighResolution: High resolution separations without ultra high pressure.

The revolutionary monolithic Chromolith® HighResolution columns are made from a single rod of high-purity monolithic silica, rather than from particles. Their unique bimodal pore structure allows the chromatographic performance to be improved significantly.

  • Speed of analysis (separations up to 9 times faster if required)
  • Separations two times faster at half the column back-pressure compared to μm columns
  • Higher sample throughput
  • Improved HPLC system security
  • Significantly increased column lifetime
  • Reduced maintenance on HPLC pump and injector seals
  • Reduced need for sample preparation as columns are very resistant to blocking (even with biological samples)
  • Column length no longer pressure limited
  • Very high separation efficiency by column coupling

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