Chromolith® High Resolution HPLC Columns
Chromolith® HighResolution: High resolution separations without ultra high pressure. The revolutionary monolithic Chromolith® HighResolution columns are made from a single rod of high-purity monolithic silica, rather than from particles. Their unique bimodal pore structure allows the chromatographic performance to be improved significantly. Speed of analysis (separations up to 9 times faster if required) Separations two…
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Great results
Analyze metabolites in urine sample
We achieve high-quality and highly reproducible results by using this column.
Review Date: 3 Oct 2022 | Merck KGaA, Darmstadt, Germany
Good quality-price ratio
Analyze small molecules
Very easy to use and good price-quality ratio.
Review Date: 29 Mar 2022 | Merck KGaA, Darmstadt, Germany
Great product to have in your tool box
analysis of small molecules in biological samples
Chromolith monolithic column offers very unique selectivity. It resolved a critical pair cleanly in our application. The low back pressure allowed us to use very fast flow rate and short gradient, which allowed nearly real-time monitoring of fast reactions. The column is reasonably durable, and handled simple acetonitrile-precipitated plasma samples well. Only slight efficiency reduction was observed (broader peaks) after almost 100 injections.
Review Date: 30 Jun 2017 | Merck KGaA, Darmstadt, Germany
It’s a wonderful experience to use this column
Low molecular binding peptide determination in plant extract
It’s a wonderful experience to use this column to check low molecular binding peptides in radionuclide (uranium) treated plant samples.
Review Date: 16 Oct 2015 | Merck KGaA, Darmstadt, Germany
Excellent HPLC
Good separation, resolution, fast, reliable and accurate.
Review Date: 2 Jan 2014 | Merck KGaA, Darmstadt, Germany
Cosmetics
Excellent, easy to use, fast analysis. We love it!
Review Date: 6 Nov 2013 | Merck KGaA, Darmstadt, Germany
amino acids quantification
It is a good column for fast and good efficiency determinations.
Review Date: 27 Aug 2013 | Merck KGaA, Darmstadt, Germany
Easy to use with sharp peek resolution.
Review Date: 17 Feb 2012 | Merck KGaA, Darmstadt, Germany
food analysis
One of our best performance columns in our laboratory. Good separation, long life and reproducible results.
Review Date: 17 Feb 2012 | Merck KGaA, Darmstadt, Germany
chromatography
This column was introduced at a time when analytical labs were trying to achieve UPLC type capability without having to purchase an UPLC. Excellent reproducibility, robust and a great column for a variety of applications.
Review Date: 16 Feb 2012 | Merck KGaA, Darmstadt, Germany
Chromolith® HighResolution: High resolution separations without ultra high pressure.
The revolutionary monolithic Chromolith® HighResolution columns are made from a single rod of high-purity monolithic silica, rather than from particles. Their unique bimodal pore structure allows the chromatographic performance to be improved significantly.
- Speed of analysis (separations up to 9 times faster if required)
- Separations two times faster at half the column back-pressure compared to μm columns
- Higher sample throughput
- Improved HPLC system security
- Significantly increased column lifetime
- Reduced maintenance on HPLC pump and injector seals
- Reduced need for sample preparation as columns are very resistant to blocking (even with biological samples)
- Column length no longer pressure limited
- Very high separation efficiency by column coupling
