Corning® Matrigel® Basement Membrane Matrix High Concentration (HC), LDEV-free, 10 mL
Corning Matrigel matrix is a solubilized basement membrane preparation extracted from the Engelbreth-Holm-Swarm (EHS) mouse sarcoma, a tumor rich in extracellular matrix (ECM) proteins, including Laminin (a major component), Collagen IV, heparan sulfate proteoglycans, entactin/nidogen, and a number of growth factors.SourceEngelbreth-Holm-Swarm Mouse TumorQuality Mouse colonies routinely screened for pathogens via Mouse Antibo…
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Works as an extracellular matrix for Cancer cells
I have found the product very useful especially in the field of cancer research. Works really good as a basement membrane to create 3D structural models for cancer cells specially.
Review Date: 12 Apr 2024 | Corning Life Sciences
Corning Matrigel matrix is a solubilized basement membrane preparation extracted from the Engelbreth-Holm-Swarm (EHS) mouse sarcoma, a tumor rich in extracellular matrix (ECM) proteins, including Laminin (a major component), Collagen IV, heparan sulfate proteoglycans, entactin/nidogen, and a number of growth factors.
Source
Engelbreth-Holm-Swarm Mouse Tumor
Quality
- Mouse colonies routinely screened for pathogens via Mouse Antibody Production (MAP) testing
- Extensive PCR testing is performed to screen for a number of pathogens
- Tested and found negative for bacteria, fungi, and mycoplasma
- Protein concentrations determined by Lowry method
- Endotoxin units measured by Limulus Amoebocyte Lysate assay
- Matrigel Matrix gel stability is tested for a period of 14 days at 37°C
- Biological activity is determined for each lot using a neurite outgrowth assay
Preparation and Storage
Store at -20°C. Avoid multiple freeze-thaws.
Application
- Cell Growth and Differentiation
- Metabolism/Toxicology Studies
- Invasion Assays
- in vitro and in vivo Angiogenesis Assays
- in vivo Angiogenesis Studies and Augmentation of Tumors in Immunosuppressed Mice
For Customers in California only: WARNING Please refer to Safety Data Sheet (SDS) Section 15 for more information regarding California Proposition 65.