CRP

The DRG:HYBRiD-XL CRP is an immunoturbidimetric assay for the quantitative in vitro diagnostic measurement of C-reactive protein (CRP) in serum and plasma (heparin and citrate).Only for use with the DRG:HYBRiD-XL Analyzer.Concentration of acute-phase proteins increase in blood as a response to inflammatory disorders (acute-phase response) (1,2). C-reactive protein (CRP), the best known member of this group, is present only at low concentration in blood of healthy individuals (< 5 mg/L), but is elevated up to 500 mg/L in the acute-phase response, caused by inflammatory processes associated with bacterial infections, post-operative conditions or tissue damage. CRP concentration increases already after 6 hours, reaching a peak after 48 hours. The measurement of CRP represents a useful laboratory test for detection of acute infection as well as for monitoring inflammatory processes in acute rheumatic (3) and gastrointestinal (4) diseases. CRP testing shows various advantages in comparison to the erythrocyte sedimentation rate (ESR) and the leukocyte count. In fact, CRP is more sensitive, shows earlier response and returns to reference range more rapidly after healing.The DRG:HYBRiD.XL CRP Kit is a immunoturbidimetric assay. It is based on an endpoint determination of the CRP concentration by photometric measurement of the antigen-antibody reaction between antibodies against human CRP and CRP that is present in the sample.