Custom & Predesigned DNA Oligos & qPCR Probes
Broad portfolio of products for classical and modern molecular technologies
Place your order directly with the manufacturer.
Fast service and great quality
Molecular Biology
Turnaround time is normally 2 days from ordering, and the data sheet gives microgram quantity, and how much to dissolve in for 100uM. We have ordered many dozens of oligos, and they have worked great in making many clones over the last few years. The one or two times over years an order was lost, they replaced the order quickly with no questions.
Review Date: 8 Apr 2022 | Merck
Great quality
Mostly PCR, cloning
High quality. We tried other companies a while ago but it only made us appreciate SIGMA oligos more - they come fast, are pure, work well, and in addition have good-quality labels showing all necessary information.
Review Date: 29 Nov 2021 | Merck
I always get satisfactory results
Protein-RNA interaction
I always preferred to order DNA and RNA oligos from Sigma. They are highly effective and specific.
Review Date: 25 Nov 2021 | Merck
Recommended.
Molecular biology
I have always achieve great quality of oligos. The website is easy to use and my order arrives a few days after I submit it.
Review Date: 19 Nov 2021 | Merck
Really good so far.
For PCR and qPCR
DNA oligos have been great so far and the Merck team are quick and easy to communicate with.
Review Date: 28 Oct 2021 | Merck
Good working Oligos!
qPCR
Completely satisfied with the qPCR results with the custom designed oligos ordered from Merck. I have ordered around 34 Oligos so far. Also the customer care services are fast and helpful.
Review Date: 27 Oct 2021 | Merck
Fast production and delivery of custom oligos
PCR
Good service for custom oligos. Generally very quick delivery times, even for custom sequences.
Review Date: 1 Oct 2021 | Merck
Great quality, quick service
PCR, Cloning and Sequencing
Great service for custom oligonucleotides, very quick turn around time!
Review Date: 21 Sept 2021 | Merck
Great!
PCR
Very effective!
Review Date: 2 Sept 2021 | Merck
Good service, good after sale service too.
Custom & predesigned DNA oligos & qPCR probes
The online platform is very easy to use and intuitive. Had very few complaints about the products received - and we have quite a good sample size to talk about. The customer service is also really good and takes a personal interest in helping you when you have any query.
Review Date: 29 Jul 2021 | Merck
We are recognized as a leading supplier of custom and predesigned DNA products as well as molecular biology tools for the global life science community. Our ability to guarantee quality and performance is directly related to our comprehensive understanding of bioinformatics, various synthesis chemistries, and manufacturing platforms; and, our investment in analytical systems and experience in methods development. Choose from our comprehensive portfolio of products, including:
- DNA Oligos in Tubes - Non-modified and modified oligos for applications including PCR, sequencing and cloning.
- DNA Oligos in Plates - Supplied in 96 or 384-well plates including many formatting options.
- Long Oligos - DNA oligo lengths from 121 to 180 bases for gene construction, microarray development and CRISPR gene editing.
- Easy™ Oligos - Normalized to 100 µM at a fixed price.
- Pure & Simple Primers - Cartridge purified primers at a fixed price.
- WellRED Oligos - For use with Beckman Coulter’s CEQ/GeXP Genetic Analysis Systems.
- iScale Oligos™ (mg & g quantity) - Larger quantities for in vivo, high throughput and commercial projects.
- Next-Gen Sequencing Oligos - Custom universal and index (barcode) adapter oligos for major sequencing platforms.
- Commercial Oligos - Custom DNA Primers, qPCR Probes, and Next-Gen Sequencing Oligos for Life Science Research Tools, Molecular Diagnostics (MDx), and Laboratory Developed Tests (LDTs).
- GMP Oligos - Custom cGMP Oligos, available with custom specifications, are Commercial Oligos (raw materials) for MDx and LDTs.
- KiCqStart® Primers - Predesigned primer pairs for quantifying gene expression by SYBR® Green I RT-qPCR.
- KiCqStart® Primers Gene Arrays - Predesigned primer pairs organized into the groups of genes that comprise common gene families.
- KiCqStart® Probe Assays - Predesigned probe assays for quantifying gene expression by RT-qPCR.
- Dual-Labeled, Internal-Quenched, Dual-Quenched Probes - Linear hydrolysis probes used in the 5’ nuclease assay with 5' reporter dyes and quenchers on the 3' end, in an internal position (between bases 9 and 10), an internal position (between bases 9 and 10) and the 3' end, or MGB linked to EDQ on the 3' end, respectively.
- Molecular Beacons - Structured hybridization probes that are not degraded during the amplification reaction (available with Locked Nucleic Acid and Black Hole Quencher™ [BHQ™]).
- LightCycler® Probes - Dual-hybridization probes designed for use in Roche™ LightCycler instruments (available with Locked Nucleic Acid and Black Hole Quencher™ [BHQ™]).
- Scorpions® Uni-Probes - Combination one-part structured probe - primers that internally hybridize to the target sequence (available with Locked Nucleic Acid and Black Hole Quencher™ [BHQ™]).
