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Diethyl pyrocarbonate

Merck KGaA, Darmstadt, GermanyD5758Available: Worldwide

≥97% (NMR)

Merck KGaA, Darmstadt, Germany

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Diethyl Pyrocarbonate (DEPC) is a chemical use to inactivate RNase enzymes and is sensitive to moisture and pH. It decomposes at 155°C, to ethanol and carbon dioxide in aqueous solution. DEPC is also sensitive to ammonia, which causes decomposition to urethane, a possible carcinogen.

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