FlowCam LO

FlowCam^® LO integrates flow imaging microscopy (FIM) and light obscuration (LO) into a single, innovative solution for particle characterization. While meeting compendial light obscuration requirements outlined in USP <787> and <788>, FlowCam LO also offers an orthogonal method to enhance quality control of subvisible particulate matter with detailed image-based analysis.

As highlighted in USP <1788>, flow imaging microscopy provides complementary morphological data and addresses challenges like undercounting and undersizing translucent particles such as proteins and other biologics. With FlowCam LO, you can acquire both light obscuration data to meet regulatory guidelines and high-quality particle images—all in one instrument and a single sample run.

Key Benefits

• Perform flow imaging and light obscuration measurements sequentially within the same instrument.
• Achieve compendial particle sizing and counting in accordance with USP <787> and <788>.
• Generate statistically significant results in under a minute with sample volumes as small as 100 μL.
• Effectively monitor and control particulate content in your formulations.

Specifications

• Particle size range: 2 μm to 70 μm; Flow imaging module: 10X (~100X magnification).
• Minimum sample volume: 100 μL.
• Sample flow rate: 0.2 mL/min.
• Camera: High-resolution CMOS (1920 x 1200 pixels), monochrome.
• Solvent compatibility: Suitable for a wide range of aqueous and organic fluids, including high-viscosity solvents and buffers.
• Ease of use: Features fully integrated VisualSpreadsheet software with optional VisualAI module for advanced analysis.