Products & ReviewLife Sciences
Gatifloxacin
Antibiotic; Inhibits bacterial DNA gyrase and topoisomerase IV
Gatifloxacin
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Gatifloxacin is a fluoroquinolone antibiotic which inhibits bacterial DNA gyrase (IC₅₀ = 0.109 µg/ml) and topoisomerase IV (IC₅₀ = 13.8 µg/ml; Takei et al.). It is much less effective against HeLa cell topoisomerase II (IC₅₀ = 265 µg/ml; Takei et al.).
MAINTENANCE AND SELF-RENEWAL
- Promotes self-renewal in cultured human and mouse embryonic stem cells (Desbordes et al.).
