GTxResolve SEC Columns
Accelerate early research, development, & release testing of GTx drug substances and products
Place your order directly with the manufacturer.
Excellent column delivering the Premier technology benefits to viral analysis
Viral aggregate + titre analysis by SE-UPLC
The Premier column showed reduced passivation, greater precision, and improved sensitivity, which resulted in a better QL. Due to a suspected reduced interaction with the column material, the peak shape was also improved resulting in a marked reduction in peak tailing. In conjunction with the associated guard column, the resolution was also improved between capsids and aggregates. Waters' care and usual manual provides detailed and easy-to-follow column care instructions.
Review Date: 19 Dec 2024 | Waters
With size exclusion chromatography (SEC), analysts can quickly assess the aggregate content, integrity, heterogeneity, and purity of gene therapy drug substances. Waters GTxResolve SEC Columns incorporate breakthrough chemistry technologies for the fast analysis of large biological analytes and a number of first-of-their-kind multi-attribute quantitation assays.
Achieve new benchmarks in quality with high resolution, low adsorption, and robust GTxResolve SEC Columns for lipid nanoparticles (LNPs), nucleic acids, and viral vector analyses that:
- Accelerate aggregate and size variant analysis with high resolution that enables detection of low-level impurities
- Deliver reproducible data necessary for platform methods
- Improve cost savings with columns that maintain a long shelf life
- Achieve low secondary interaction enabling low MALS noise
- Provide low adsorption hardware necessary with biologics to enhance recovery
