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Invitrogen™ NucGreen™ Dead 488 ReadyProbes™ Reagent

High-affinity DNA stain for studying cell viability and cytotoxicity

Thermo Fisher Scientific

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Average Rating 5.0

Application Area:

Cell and nuclei stain

This is a great product for identifying dead cells or isolating nuclei. We use it for nuclei isolations and single nuclei sequencing preps. Works with imaging scopes or the countess II cell counter.

Review Date: 17 Dec 2018 | Thermo Fisher Scientific

NucGreen Dead 488 ReadyProbes Reagent is a cell-impermeant stain that emits exceptionally bright, green fluorescence when bound to DNA. Cells that have lost plasma membrane integrity are stained within minutes, making this an extremely useful stain to estimate live/dead cell ratios and to measure cytotoxicity in kinetic live-cell assays. It is also suitable for staining nuclei in fixed cell preparations and tissue sections.


  • Exceptionally bright green fluorescence upon binding to DNA
  • Rapid staining of damaged, dead, or fixed cells without wash steps
  • Ready-to-use liquid formulation in convenient dropper bottle—no need to dilute, weigh, or pipette
  • Stable at room temperature—keep handy at your scope

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