IONSCAN-LS™
The IONSCAN-LS detects and quantitates trace analytes using ion mobility spectrometry (IMS). Ultra-fast analysis with the IONSCANLS offers the advantages of simplicity, selectivity sensitivity, atmospheric pressure operation and ease-of-use. These features, together with 21 CFR Part 11 compliance, make it ideal for use in pharmaceutical applications. The IONSCAN-LS offers two different sample introduction methods: Thermal, des…
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Review Date: 1 Apr 2022 | Smiths Detection
Review Date: 13 Jun 2011 | Smiths Detection
The IONSCAN-LS detects and quantitates trace analytes using ion mobility spectrometry (IMS). Ultra-fast analysis with the IONSCANLS offers the advantages of simplicity, selectivity sensitivity, atmospheric pressure operation and ease-of-use. These features, together with 21 CFR Part 11 compliance, make it ideal for use in pharmaceutical applications.
The IONSCAN-LS offers two different sample introduction methods: Thermal, desorption from a filler and high performance injection (HPI). The HPI and flow programming with split /splitless injection capabilities. The availability of these two techniques maximizes the breadth of compounds that can be analyzed successfully. More than 80 percent of active pharmaceutical ingredients investigated to date are amenable to IMS analysis.
The IONSCAN-LS can analyze sample over a concentration range of about three orders of magnitude. A typical limit of quantitation (LOQ) is on the order of 0.1ug/mL. LOQs as low as 0.002ug/mL have been observed for some compounds.
The IONSCAN-LS is equipped with an auto sampler allowing the user to run automatic methods that have been pre programmed into the IONSCAN-LS’s IMStation software. With the auto sampler, sequential analyses are typically run in 30-60 seconds each, a critical time-saver in applications such as cleaning validation.
