ioSkeletal Myocytes Human iPSC-derived skeletal myocytes
Introducing highly-defined, consistent, and reliable human muscle cells for research, disease modeling, and high throughput screening across areas such as muscle, neuromuscular, and associated metabolic disorders. ioSkeletal Myocytes, part of the bit.bio ioCells portfolio, have been reprogrammed from human induced pluripotent stem cells (iPSCs) using bit.bio's precise reprogramming technology: opti-ox™
Highly-defined, consistent and reliable
Express key myofilament proteins in days
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bit.bio’s opti-ox cellular reprogramming allows for human pluripotent stem cells, within days, to convert into skeletal myocytes, providing a high-quality, easy-to-use, cellular model.
Skeletal myocytes demonstrate robust expression of components of the contractile apparatus and form striated, multinucleated, myocytes by Day 10 post revival, that contract in response to acetylcholine.
Unprecedented batch-to-batch consistency allows for their use in demanding screening applications where small changes need to be detected against background noise.
