Lgals1 (gal1) Knockout Rat
Galectins have been implicated in inflammation and cancer, and are useful targets for development of new anti-inflammatory and anticancer therapies. LGALS1 (GAL1) may act as an autocrine negative growth factor that regulates cell proliferation. Lgals1 (gal1) Knockout Rat Characteristics: Homozygous knockout rats display loss of LGALS1 protein via Western blot Background Strain: Sprague-Dawley Research Applications:…
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Galectins have been implicated in inflammation and cancer, and are useful targets for development of new anti-inflammatory and anticancer therapies. LGALS1 (GAL1) may act as an autocrine negative growth factor that regulates cell proliferation.
Lgals1 (gal1) Knockout Rat Characteristics:
- Homozygous knockout rats display loss of LGALS1 protein via Western blot
- Background Strain: Sprague-Dawley
Research Applications:
- Rheumatoid arthritis
- Inflammation/Autoimmune disorders
- Asthma
- Multiple sclerosis
- Thrombosis/Cardiac fibrosis
- Vascular defects
- Platelet defects/Platelet aggregation
- Renal dysplasia
- Crohn's disease
- Colitis