Lumipulse® G NfL Blood (RUO)
Immunoassay to be used with the automated LUMIPULSE G System for the quantitative measurement of neurofilament light (NfL) in human plasma and serum.
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Neurofilament light (NfL) is an intermediate filament protein found specifically in the neuronal cytoskeleton. It can be released into the extracellular space through axonal degradation, and it has been shown that varying NfL levels are an indicator of neuroaxonal damage, irrespective of the cause, and can therefore be associated with a variety of neurological diseases such as multiple sclerosis, amyotrophic lateral sclerosis, frontotemporal dementia or Alzheimer's disease, as well as acute situations such as traumatic brain injury and others.
