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MACS® Matchmaker

With the MACS® Matchmaker you can experience a robust platform that delivers quantitative data on binder affinity, kinetics, and specificity in complex samples. Unlock new possibilities in your research today – because every target deserves its perfect match!

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Lino Biotech – A Miltenyi Biotec Company

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The MACS Matchmaker is the first commercial instrument using focal molography technology, revolutionizes biological interaction measurement. This innovative approach provides a direct, undisturbed view of molecular dynamics in their natural state, without the need for labels, overcoming traditional research limitations like signal disturbance and non-specific binding. It's not just an instrument; it's a gateway to a new era of life sciences research, enabling real-time observation and quantification of biological processes. It is transforming biological research, paving the way for more accurate, efficient, and straightforward studies, heralding a groundbreaking future in molecular interaction research.

Key benefits of the system include:

  • Interaction studies in complex samples: in vivo like measurement and saving time by eliminate the hassle of sample pre-purification
  • Automated acquisition: Use the MACS® Sampler for fully unattended runs in combination with up to 2 x 384 well plates
  • Multiplexed assays: Characterize 64 interactions simultaneously, significantly reducing experiment times
  • Label-free analsis: Focal molography is a label-free interaction technology able to characterize a plurality of important interactions.
  • Pico-molar sensitivity: Characterize even small proteins or peptides at pM sensitivity in complex biological matrices.
  • Drift-free data: Experience robust and more reliable data with minimized artifacts with a drift of <0,05 pg/mm2/min. Perfect for characterizing low-off rate binders.

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