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Monocyte Distribution Width Sepsis Risk Marker

Host response biomarker of sepsis risk

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Beckman Coulter Clinical Diagnostics

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Monocyte Distribution Width (MDW) is the only regulatory-cleared hematological biomarker that helps to establish risk of severe infection and sepsis in adult patients in the emergency department. MDW is a measure of increased morphological variability of monocytes in response to bacterial, viral or fungal infections.

MDW is reported automatically as part of a routine CBC with Differential test using the Early Sepsis Indicator (ESId) application*, which enables automatic reporting with no workflow changes or need to order an additional test.

What Makes MDW Unique?

  • Monocyte Activation is a common physiological signal in risk of severe infection and sepsis
  • MDW is backed by rigorously designed patient trials and several rounds of in-depth review to meet the standards required for regulatory-clearance and CE mark
  • MDW has been studied for the past decade with more than 60 peer-review publications and 30,000+ patients, confirming the robustness and reproducibility of MDW performance in different patient populations
  • MDW helps reduce diagnostic uncertainty. It is available early to enhance the initial risk assessment and potentially shift your clinical decision point helping clinicians escalate or de-escalate care

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