Products & ReviewLife Sciences

NanoBRET™ Target Engagement BET BRD Assays

Promega Corp.N2131, N2130

The NanoBRET™ Target Engagement (TE) Intracellular BET BRD Assay measures compound binding at select BET bromodomain target proteins within intact cells. This target engagement assay is based on the NanoBRET™ System, an energy transfer technique designed to measure molecular proximity in living cells

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Average Rating 4.3

|1Scientists have reviewed this product

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The nanoBRET assay is set-up for several projects in our company and we recommend it!

 

Average Rating 4.3

Application Area:

evaluate compounds for their inhibitory activity

The nanoBRET assay has the additional advantage of using a ratiometric readout, allowing intra-well normalization and showing increased assay quality. It enables medium/high quality results depending on the constructs used. It makes the link between in vitro and in vivo assays.

Review Date: 16 Apr 2018 | Promega Corp.

The NanoBRET™ Target Engagement (TE) Intracellular BET BRD Assay measures compound binding at select BET bromodomain target proteins within intact cells. This target engagement assay is based on the NanoBRET™ System, an energy transfer technique designed to measure molecular proximity in living cells

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