nanoEase M/Z NanoFlow LC-MS Columns

Generate high-quality peptide and protein separations

The ability to reproducibly generate high-quality peptide and protein separations is critically important in proteomics research and biopharmaceutical characterization. Waters Ethylene-Bridged Hybrid (BEH), Charged Surface Hybrid (CSH), and High Strength Silica (HSS) peptide and protein nano columns help address these demanding needs. Combining columns with low retentive trap columns results in highly efficient separations with an increased number of peak identifications.

Waters nano- and microflow LC-MS columns are specifically designed for low-dispersion nano LC systems. The selected stationary phases of these analytical columns fully leverage the separation power of sub-2–µm particle technology at flow rates between 100 nL/min and 50 µL/min, withstanding 15,000 psi, and have an inner diameter between 75 µm – 300 µm. This delivers the efficiency and selectivity required for complex separations like the discovery of low abundance species, peptide mapping, protein identification, and biomarker discovery.