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Neurodazine
Inducer of neural differentiation
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Neurodazine is a cell-permeable tri-substituted imidazole and neurogenic agent (Williams et al. 2007).
DIFFERENTIATION
- Induces neurogenesis of C2C12 myoblasts as well as mature human muscle cells, marked by upregulation of neural genes (Williams et al. 2007; Williams et al. 2008).
- Induces neurogenesis and prevents astrocyte differentiation of P19 mouse embryonic carcinoma cells (Kim et al.).
- Induces neuronal differentiation of human (SH-SY5Y) and mouse (Neuro-2a) neuroblastoma cells, and mouse NIH3T3 fibroblast cells (Halder et al.).