Octave BIO

Octave BIO is an innovative multi-column chromatography (MCC) benchtop instrument designed for the method development and scale-up of productivity-intensified large-scale purification of biological probes. It supports the transfer of batch methods to continuous counter current chromatography, which usually is accompanied by a massive reduction of consumable consumption, e.g. 90% resin saving for Protein A or L applications.

Features and benefits:

• Columns: 1 – 8
• Flow rates: 1 – 300 ml/min
• Sensors: 4 Dual-UV detectors, 4 conductivity monitors, 4 pH sensors
• Fractionation: Signal triggered fractionation via 3-way-valve
• Operation versatility: Step mode, isocratic mode (SMB), batch-mode, parallel LC, gradient-mode
• User support: Method wizard guides from batch to continuous operation
• Ease of operation: Clear software surface enables fast technique adaption
• Classic applications: Capturing and polishing of monoclonal antibodies and antibody fragments