PATfix mRNA Platform
Rapid at-line analytical chromatography solution for all stages of mRNA production, purification, and quality assessment.
Place your order directly with the manufacturer.
The PATfix® mRNA Platform is a chromatography-based system designed for rapid and precise analysis of mRNA products throughout the manufacturing process. It enables at-line monitoring of critical quality attributes such as mRNA integrity, capping efficiency, purity, and size with minimal sample preparation—requiring only simple dilution. This platform supports real-time decision-making during process development, scale-up, and quality control.
Equipped with sensitive detectors the PATfix® mRNA Platform provides detailed insights into the molecular characteristics of mRNA drug products. Its flexible software architecture allows secure, remote access to data, facilitating collaboration and data-driven process optimization.
Key Features & Benefits
- Fast requiring only sample dilution
- Monitors capping efficiency, integrity, purity, and size distribution in a single run
- Sensitive detectors suite for high-resolution mRNA characterization
- Enables real-time, at-line monitoring to accelerate process development
- Secure, client-server software supports remote data access and collaboration
Applications
- Monitoring in vitro transcription (IVT) reactions
- Quality control during mRNA manufacturing and purification
- Assessment of capping efficiency and RNA integrity
- Process development and scale-up of mRNA therapeutics
- Support for regulatory submissions with robust analytical data
