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Seahorse XF Plasma Membrane Permeabilizer

The Agilent Seahorse XF Plasma Membrane Permeabilizer (PMP) is a proprietary reagent that permeabilizes intact cells in culture. It selectively targets the cellular plasma membrane while leaving the mitochondrial membrane intact. This selectivity enables the detailed characterization of key components in mitochondrial function including transporters, enzymes, and electron transport chain complexes.

Agilent Technologies

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The Agilent Seahorse XF Plasma Membrane Permeabilizer (PMP) is a proprietary reagent that permeabilizes intact cells in culture. It selectively targets the cellular plasma membrane while leaving the mitochondrial membrane intact. This selectivity enables the detailed characterization of key components in mitochondrial function including transporters, enzymes, and electron transport chain complexes.

Features

  • Selectively targets the cellular plasma membrane for permeabilization

  • Study mitochondrial function without isolating mitochondria

  • 1.0 nM works for most cell types, meaning that minimal optimization is required

  • The XF PMP reagent provides consistent results in every assay

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