Single SOMAmer Reagents (SSRs)
A new antibody alternative for affinity-based assays
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Single SOMAmer™ Reagents (SSRs) are a new class of synthetic affinity reagents for protein detection workflows. They work in confirmatory proteomic applications such as ELISAs, pull-down assays.
Engineered with high specificity and slow off-rates SSRs overcome many common limitations of traditional antibodies, including poor batch-to-batch reproducibility, instability, and high production variability.
Produced entirely through chemical synthesis, SSRs offer a long shelf life, are thermally stable, reproducible, and animal-free – aligning with modern ethical and regulatory standards.
Their small size (8–15 kDa vs. ~150 kDa antibodies) enables better access to epitopes and reduces nonspecific binding, making them ideal for low-abundance or structurally challenging protein targets. With nearly 11,000 unique SSRs available off-the-shelf (That’s half the human proteome!), researchers can rapidly integrate them into existing workflows without the delays associated with custom antibody development.
Whether used when antibodies fail or to expand target coverage, SSRs provide a modern solution to accelerate research and development in both academic and translational settings.
