Products & ReviewLife Sciences
Sinomenine
Anti-inflammatory
Sinomenine (Hydrochloride)
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Sinomenine is a natural plant alkaloid commonly used to alleviate inflammation associated with rheumatoid arthritis (Wang and Li). It impairs signaling through Nuclear factor-kappaB (NF-κB; Sun et al.; Wang and Li) and enhances the bioavailability of some compounds, at least in part through an inhibition of drug export by transporters like P-glycoprotein (Kesarwani et al.; Liu et al.).
MAINTENANCE AND SELF-RENEWAL
- Promotes self-renewal in cultured human and mouse embryonic stem cells (Desbordes et al.).
