Special Application TSKgel RPC Columns
The TSKgel OligoDNA RP and TSKgel TMS-250 columns incorporate 5 μm or 10 μm spherical porous silica with 250Å pores to allow unhindered access by large oligonucleotides and proteins respectively.
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Great results. Very satisfied with the investment.
Analyze of largenucleotides
Easy to use and store.
Review Date: 19 Jul 2022 | Tosoh Bioscience
Unfortunately, in the end twe chose a different column.
Antibody PepMap
The column has worked so far, but due to some problematic peaks, the choice fell on a different column.
Review Date: 19 Mar 2021 | Tosoh Bioscience
Great results and resolutions.
Size exclusion chromatography for separation and characterisation
It was the right decision. These columns are the perfect choice for this application. Easy to use and store. Price/value really good.
Review Date: 19 Mar 2021 | Tosoh Bioscience
Good results but lifetime vs. cost is often not well balanced.
HT SEC applications for therapeutic proteins
Easy to use and good separation. But often experienced significant problems with lifetime.
Review Date: 19 Mar 2021 | Tosoh Bioscience
Great results, especially for SEC analysis.
Protein analytics with size exclusion chromatography
Excellent performance of methods and good reproducible results.
Review Date: 19 Mar 2021 | Tosoh Bioscience
Very good for proteins.
Analysis of Antibody-Drug Conjugates
These columns are a very good choice for ADC analysis as well as mAb and other protein analysis - reproducible results, well-shaped peaks and retention times stability are the main advantages for me, as an end user.
Review Date: 7 Feb 2020 | Tosoh Bioscience
The TSKgel OligoDNA RP and TSKgel TMS-250 columns incorporate 5 μm or 10 μm spherical porous silica with 250Å pores to allow unhindered access by large oligonucleotides and proteins respectively.
Product highlights
TSKgel OligoDNA RP:
- Contains a monomeric C18 bonded phase that is not endcapped.
- Available in 4.6 mm id and 7.8 mm id (both 15 cm length)
TSKgel TMS-250:
- Exhaustively and repeatedly reacted with trimethyl silyl groups.
- Standard nomenclature designates the bonded phase as C1.
- Available in 4.6 mm id x 7.5 cm length.
Product Applications
TSKgel OligoDNA RP:
- Specialty column for analysis and preparative purification of oligonucleotides (up to 500-mer), RNA and DNA-fragments.
TSKgel TMS-250:
- Specialty columns for protein separations.
- The “wide-pore” TMS-250 packing can accommodate large proteins, such as aldolase (158 kDa).
