Stanniocalcin 2 ELISA
In breast cancer STC2 is induced by estrogen and STC2 expression levels correlate with levels of estrogen receptor. STC2 function in different cancers may involve regulation of cell proliferation, neoplastic transformation and endothelial invasion. STC2 also plays a role in epithelial-mesenchymal transition by activation of MAPK/ERK signaling in hypoxic ovarian cancer cells.
In breast cancer STC2 is induced by estrogen and STC2 expression levels correlate with levels of estrogen receptor. STC2 function in different cancers may involve regulation of cell proliferation, neoplastic transformation and endothelial invasion. STC2 also plays a role in epithelial-mesenchymal transition by activation of MAPK/ERK signaling in hypoxic ovarian cancer cells. STC2 is upregulated in several cancers including, gastric cancer, lung cancer, renal cell carcinoma, colorectal cancer, castration-resistant prostate cancer and cervical cancer. Serum STC2 levels may serve as a valuable research tool for diagnosis and prognosis of several cancers and growth defects.
The Ansh Labs’ Stanniocalcin-2 ELISA is a quantitative two-step sandwich type immunoassay. STC2 plays a role in epithelial-mesenchymal transition by activation of MAPK/ERK signaling in hypoxic ovarian cancer cells. STC2 function in different cancers may involve regulation of cell proliferation, neoplastic transformation and endothelial invasion.
- Total 3 hour incubation at room temperature
- Wide dynamic range of 0.85-55 ng/mL
- Sensitive to 0.033 ng/mL
The antibody pair used in the assay is specific to Stanniocalcin-2. Other related molecules did not show any significant cross-reaction.
Research Use Only within the United States. Ansh Labs is an FDA registered manufacturer of diagnostic test kits, antibodies, antigens, and proteins.