Products & ReviewLife Sciences
Swift Accel-NGS® Adaptase™ Module
Prepare Single-Cell Methyl-Seq Libraries
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The Accel-NGS Adaptase Module constructs NGS libraries from bisulfite-converted, single-stranded DNA from single cells. Because bisulfite treatment results in lower quantity and quality DNA, the module is optimized to maximize the recovery of DNA containing uracil residues and low concentrations of AT-rich template. The resultant libraries consistently exhibit superior complexity with reduced composition bias to provide a more faithful representation of the methylome.
Features:
- Increased (> 2-fold) mapping rate
- Larger (> 2-fold) library insert size
- Workflow uses a single random priming cycle
- Three-dimensional indexing for high-throughput sequencing
Benefits:
- Greater data output per run and reduced sequencing cost
- Efficient use of sequencing reads and greater data output per sequencing cluster
- Easier low bias workflow 384-plex single-cell sequencing for large volume sequencing instruments
