Swift Lynch Syndrome Panel
Sequence key genes implicated in Lynch Syndrome
The supplier does not provide quotations for this product through SelectScience. You can search for similar products in our Product Directory.
The Accel-Amplicon Plus Lynch Syndrome Panel is the NGS multigene panel to identify mutations in DNA Mismatch Repair (MMR) genes. It offers comprehensive and exon-level hotspot coverage of 4 clinically-relevant genes: MLH1, MSH2, MSH6 and PMS2. And with sensitivity down to 1% allele frequency, now you can identify both germline and somatic mutations in the same panel. But that’s just the beginning. This panel is modular, allowing you to add on focused content to achieve your most optimal design. Either combine pre-validated content from our existing menu, such as Colorectal Cancer Panel or add your own targets. We’ll work alongside you to design your assay and then Swift will optimize and wet-bench validate its performance before shipping it to you.
Key features include:
- Robust performance on cell-free DNA and FFPE samples starting with as little as 10 ng input.
- Sensitive detection of rare variants down to 1% allele frequency.
- Easy, single-tube assay with sequence ready libraries in 2 hours.
- Streamlined analysis with new bioinformatics tools including Primerclip or Genialis.
- Compatible with all Illumina sequencers
