T7 Endonuclease I
T7 Endonuclease I recognizes and cleaves non-perfectly matched DNA, cruciform DNA structures, Holliday structures or junctions, heteroduplex DNA and more slowly, nicked double-stranded DNA.
T7 Endonuclease I
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Reproducable and fast results
Gene editing
The product always worked excellently without any problems. Also, we always have reproducible data. Moreover, the company provided an easily understandable protocol for the product. More importantly the product works faster than other alternatives.
Review Date: 20 Oct 2023 | New England Biolabs Inc.
T7 Endonuclease I recognizes and cleaves non-perfectly matched DNA, cruciform DNA structures, Holliday structures or junctions, heteroduplex DNA and more slowly, nicked double-stranded DNA. The cleavage site is at the first, second or third phosphodiester bond that is 5´ to the mismatch. The protein is the product of T7 gene 3.
Highlights
- Isolated from a recombinant source
- Supplied with 10X Reaction Buffer
- Recognizes non-perfectly matched DNA
Product Source
An E. coli strain that carries a fusion of maltose binding protein and T7 Endonuclease I (T7 Endo I).
This product is related to the following categories:
- Mutation Detection Reagents and Kits
- Genome Editing Products
- Exonucleases and Non-specific Endonucleases Products
- DNA Repair Enzymes
- Structure-specific Endonucleases Products
This product can be used in the following applications:
- Whole Genome AmplificationMultiple Displacement Amplification
- Genome Editing Applications
