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Thermo Scientific™ pH Gradient Buffer Solutions

Thermo Fisher ScientificIQLAALGABXFAITMBBM

pH Gradient Buffer Solutions - Simple method development for charge variant characterization Traditionally cation-exchange chromatography using salt gradients has been successfully used to characterize MAb charge variants. However, additional effort is often required to tailor the salt gradient method for individual charge variants. Thermo Scientific™ pH buffer solutions and kits can be used to generate highly reproducible, li…

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Average Rating 4.3

|2Scientists have reviewed this product

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Great price point and in stock

 

Average Rating 4.3

Application Area:

Calibrating pH electrodes

The product is easy to use and I get reproduceable results. The price point is great and the product is typically in stock. I typically get my buffers from Thermo Fisher as they are my trusted source.

Review Date: 15 May 2023 | Thermo Fisher Scientific

The buffer solution accuracy is very precious.

 

Average Rating 4.3

Application Area:

Analyze water samples and acid samples

The manufacturer's material gives tremendous performance during analysis.

Review Date: 27 Mar 2021 | Thermo Fisher Scientific

pH Gradient Buffer Solutions - Simple method development for charge variant characterization

Traditionally cation-exchange chromatography using salt gradients has been successfully used to characterize MAb charge variants. However, additional effort is often required to tailor the salt gradient method for individual charge variants. Thermo Scientific™ pH buffer solutions and kits can be used to generate highly reproducible, linear pH gradients using cation-exchange chromatography.

This generic, LC-based platform approach saves time in method development and facilitates method transfer to QA/QC for a wide range of MAb charge variants. Unlike traditional salt gradients, it is possible to predict the pI and the expected retention of the charge variants and use a narrow pH range to get a higher resolution separation.

pH Gradient Buffer Solutions Features:

  • Proprietary buffer formulations enable fast,robust and reproducible pH gradients that are simple to optimize and easily automated
  • Ready to usewith existing LC columns and systems, without the need for time-consuming mobile phase adjustments
  • Applicable to the majority of MAbs

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