Products & ReviewLife Sciences
Tumor Necrosis Factors (TNF)
Recombinant TNF superfamily ligands and receptors, pivotal for research into apoptosis, cell survival, inflammation, and immune regulation.
Tumor Necrosis Factors (TNF)
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The TNF superfamily consists of type II transmembrane proteins that can be cleaved into soluble cytokines. They trigger signaling pathways that lead to diverse outcomes, including programmed cell death (apoptosis) and inflammation. These proteins are crucial for understanding immune diseases and developing related therapeutics.
Key Features & Benefits:
- Includes TNF-α, TRAIL, FasL, and their Receptors
- Functional Grade for Apoptosis and NF-κB Activation Assays
- Available in Soluble and Membrane-Bound Mimetic Formats
- High Purity and Activity
Relevant Applications:
- Apoptosis and Cell Survival Signaling Studies
- Inflammation and Septic Shock Research
- Autoimmune Disease Drug Discovery
- Cancer Biology (e.g., TRAIL-induced apoptosis)
