Products & ReviewLab Automation

USP 4 / Apparatus 4

USP Apparatus 4 Product Details:• Cells designed for MR, CR and ER tablets, capsules, suppositories, powders, pellets, APIs, implants, medical devices, ophtalmic devices, drug eluting stents, creams, gels, suspensions, microspheres, liposomes and nanospheres • Suitable for R&D and QC, manual and automated sampling, firmware or software driven, linked to UV, UVFO (UV Fiber Optic) and fraction collector for HPLC • Evolution of t…

The supplier does not provide quotations for this product through SelectScience. You can search for similar products in our  Product Directory.

Ease of Use
After Sales Service
Value for Money
Write your own review

USP Apparatus 4 Product Details:

• Cells designed for MR, CR and ER tablets, capsules, suppositories, powders, pellets, APIs, implants, medical devices, ophtalmic devices, drug eluting stents, creams, gels, suspensions, microspheres, liposomes and nanospheres
• Suitable for R&D and QC, manual and automated sampling, firmware or software driven, linked to UV, UVFO (UV Fiber Optic) and fraction collector for HPLC
• Evolution of the original Flow-Through Cell system designed by Dr Langenbucher and SOTAX 35 years ago
• Compliant to USP, EP and JP for Small Volume Dissolution and Poorly Soluble Compound Testing under Sink conditions

With the Flow-Through Cell, fresh media passes continuously across the dosage form. This is called an open loop system. A semi-automated system allows samples to be taken simultaneously and collected in a fraction collector or analyzed directly by UV. Complete fractions or aliquotes can be collected in an Off-line open system. It is also possible to collect samples and analyze them. Dissolution can also be analyzed in situ in a Fiber Optics Dissolution system also called UVFO.

USP 4 Fixed and Small Volume Dissolution/Elution Testing...For small or fixed volume testing, the flow through cell can re-circulate the media across the dosage form. This is called a closed loop system. This can be an on-line closed loop with UV or UV Fiber Optic, micro volume autosampler, and even a manual sampling syringe.

The validation of the USP 4 Dissolution Testing system according to the regulations can be done by a SOTAX specially trained service engineer. The USP requires the flow rate and temperature to be qualified.

Product Overview

Links