Drug discovery > Basic Research Products & Reviews

Products, services, reviews and techniques used in the preliminary investigations of the disease; the cell biology, genetics and protein pathways using tissue culture, cloning and imaging.

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Seahorse XF Mito Tox Assay Kit

Agilent Technologies

The kit is designed to use with Agilent Seahorse XF Pro analyzer for easily identifying drug-induced mitochondrial toxicity, to de-risk your drug pipeline.  It provides high sensitivity and specificity, reducing false positive and false negatives.  It is applicable to screen compound libraries with a throughput of 80 compounds per plate.  Assay performance metrics Z’ of > 0.5 is achievable following our assay workflow. 

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Revident quadrupole time-of-flight LC/MS (LC/Q-TOF)

Agilent Technologies

To stay competitive and adjust to changing industry requirements, you need evolved instrumentation with complete workflow solutions to meet current and future challenges. You must ensure that your lab can respond to emerging and unexpected contaminants with broader screening and retrospective analysis. The Agilent Revident LC/Q-TOF answers these challenges by maximizing time and productivity with sophisticated instrument inte…

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Resolution ctDx FIRST Assay

Agilent Technologies

Agilent Resolution ctDx FIRST is a liquid biopsy NGS assay optimized for cancer genomic profiling. ctDx FIRST is an FDA approved companion diagnostic to KRAZATI™ (adagrasib) for the detection of KRAS G12C in non-small cell lung cancer (NSCLC) and provides tumor mutation profiling for single nucleotide variants (SNVs) and deletions in the EGFR gene.

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  • Best New Clinical Assay or Kit of the Year

BioTek 406 FX Washer Dispenser

Agilent Technologies

The Agilent BioTek 406 FX washer dispenser is a compact instrument offering fast, plate washing along with up to six reagent dispensers. The Dual-Action manifold optimizes washing for a variety of cell types, in addition to biomagnetic protocols in plate configurations from 96- to 1536-well. Non-contact plate dispensing capabilities offer flexibility, including up to four syringe pumps and two peristaltic pump dispensers enab…

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Seahorse XF T Cell Metabolic Profiling Kit

Agilent Technologies

The Agilent Seahorse XF T Cell Metabolic Profiling kit allows for robust and accurate measurements of both glycolytic and mitochondrial activities in T cell populations, providing a complete picture of T cell energy metabolism. These measurements can be linked to antitumor properties of T cell therapy products and are therefore valuable in designing and optimizing therapy development processes to improve T cell persistence or…

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Agilent Seahorse Analytics

Agilent Technologies

Agilent Seahorse Analytics is the newest data analysis application for Agilent Seahorse XF Analyzer products. Seahorse Analytics is built in the cloud, meaning there is no software for you to install, update, or manage. Learn how Seahorse Analytics can make your data analysis experience easier and more enjoyable. Register for a free account and start uploading your assay result files now.

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Seahorse XF Plasma Membrane Permeabilizer

Agilent Technologies

The Agilent Seahorse XF Plasma Membrane Permeabilizer (PMP) is a proprietary reagent that permeabilizes intact cells in culture. It selectively targets the cellular plasma membrane while leaving the mitochondrial membrane intact. This selectivity enables the detailed characterization of key components in mitochondrial function including transporters, enzymes, and electron transport chain complexes.

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Seahorse XF Hu T Cell Activation Assay Kit

Agilent Technologies

Agilent Seahorse XF Hu T Cell Activation Assay Kit measures human (Hu) T cell activation response within several minutes of stimulation using Seahorse XF Analyzers. This is accomplished via measuring proton efflux rates (PER) associated with glycolytic pathway-dependent energy production, and is built on the principle that T cell activation is accompanied by a rapid switch in cellular energy production and intermediate demand…

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Seahorse XF Palmitate Oxidation Stress Test Kit and FAO Substrate

Agilent Technologies

The Agilent Seahorse XF Palmitate Oxidation Stress Test Kit provides validated reagents to measure long chain fatty acid oxidation (FAO) via assessing changes in oxygen consumption (OCR) in intact cells. The kit includes the XF Palmitate-BSA FAO Substrate, L-carnitine, etomoxir, as well as oligomycin, FCCP, and rotenone/antimycin A to determine the intrinsic rate and capacity of a cell to oxidize palmitate in the absence or l…

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Cell Culture & Imaging Microplates

Agilent Technologies

Agilent offers a new microplate product line to support cell culture and imaging. These high-quality polystyrene products provide superb optical clarity and comply with ANSI standards for compatibility with automated processing systems. TC surface treatment enhances cell attachment while the included lid maintains a sterile growth environment with low risk of cross-contamination. The product designs feature easy stacking, alp…

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