Separations is a fundamental scientific discipline focused on the isolation and purification of components from mixtures. Through techniques such as chromatography, distillation, and filtration, separations scientists separate substances based on their physical or chemical properties. This field plays a crucial role in various industries, including pharmaceuticals, food and beverage testing, environmental science, materials research, and more. Explore how separations techniques enable precise analysis, quality control, and the development of innovative products.
Bond Elut PBA is a unique silica SPE sorbent containing a phenylboronic acid functionality that can retain analytes through a reversible covalent bond. This very strong covalent retention mechanism enables high specificity and cleanliness. The boronate group has a strong affinity for cis-diol containing compounds, such as catechols, nucleic acids, some proteins, carbohydrates, and PEG compounds.
Bond Elut PCB is a specially designed sorbent that allows for the facile extraction of polychlorinated biphenyl (PCB) compounds from various matrices. Desired analytes can be loaded and eluted using a simple, single solvent method before analysis by GC/ECD.
Bond Elut PH is a nonpolar bonded silica material, which exhibits a different selectivity to alkyl or aliphatic functionalized phases, such as C8 or cyclohexyl. The electron density present in the aromatic ring affords an enhancement in the retention of conjugated or aromatic ring-containing analytes due to desirable pi-pi interactions.
Bond Elut Plexa PAX sets the new performance standard in analyte cleanup and reproducibility for polar and non-polar acidic analytes. Existing polymeric anion-exchange sorbents can exhibit a broad range of ion exchange capacity from batch to batch. This leads to nonreproducible methods and compromised data.
Bond Elut PPL is a styrene-divinylbenzene (SDVB) polymer that has been modified with a proprietary nonpolar surface. PPL will retain even the most polar classes of analytes, including phenols. The large particle size allows ease of flow for viscous or particulate-rich water samples, while the high surface area and strong hydrophobicity ensure reproducible extractions with high recoveries upon elution.
Bond Elut SAX is a strong anion-exchange sorbent ideally suited for the extraction of compounds, such as carboxylic acids, which may not retain effectively on weak anion-exchange sorbents.
Bond Elut SCX is a strong cation exchanger with a very low pKa. Although the pKa is similar to Bond Elut PRS, the presence of the benzene ring in the functional group increases the potential for nonpolar interactions. This nonpolar characteristic becomes particularly important when conducting ion exchange from aqueous systems, where selectivity towards compounds exhibiting cationic and nonpolar character is seen.
Native silica is generally regarded as the most polar SPE sorbent available. Bond Elut SI is particularly effective at separating compounds with a very similar structure. Applying the analytes in a non-polar solvent, then increasing the solvent polarity by increasing the concentration of a polar modifier, such as THF or ethyl acetate, delivers effective separations.
Simplify sodium sulfate mediated drying steps by using cartridges prepacked with ACS grade, granular anhydrous sodium sulfate. Available in three formats (LRC, Bond Elut Jr, and straight barrels).
The same Bondesil sorbent packed into the industry-leading Bond Elut cartridges is available in bulk for large-scale purification or packing custom cartridges.
