Drug discovery > Target Discovery Products & Reviews

Our single-stranded DNA binding standard is a helix-destabilizing E. coli protein. The 75.6-kD protein is essential for replication, recombination, and repair processes.

The HybriZAP-2.1 two-hybrid vector system, a eukaryotic system to detect proteinprotein interactions in vivo, provides a method for the rapid identification of genes encoding proteins that interact with a bait protein. The system is based on the ability to separate eukaryotic transcriptional activators into two separate domains, the DNA binding domain (BD) and the transcriptional activation domain (AD).  Detects protein-prote…

The High-Sensitivity beta-Galactosidase Assay Kit provides an easy, rapid, and sensitive method for determining the beta-galactosidase activity in the lysates of cells transfected with a beta-galactosidase expression construct.  Rapid, simple and sensitive  >= 10-fold increase in sensitivity over ONPG-based kits  Reduces amount of cell extract needed for assay  Useful for cells that are difficult to transfect and have l…

The pET E.coli expression system is a widely used in vivo bacterial expression system due to the strong selectivity of the bacteriophage T7 RNA polymerase for its cognate promoter sequences, the high level of activity of the polymerase, and the high efficiency of translation mediated by the T7 gene.  Tightly controlled T7 RNA polymerase-based gene expression in     E.coli    High-level expression upon induction  Convenien…

The pET E.coli expression system is a widely used in vivo bacterial expression system due to the strong selectivity of the bacteriophage T7 RNA polymerase for its cognate promoter sequences, the high level of activity of the polymerase, and the high efficiency of translation mediated by the T7 gene.  Tightly controlled T7 RNA polymerase-based gene expression in     E.coli    High-level expression upon induction  Convenien…

The InterPlay adenoviral TAP System combines our unique tandem affinity purification (TAP) system with our exclusive adenoviral gene delivery system, the AdEasy Adenoviral Vector System for enhanced gene delivery to a broader range of mammalian cells, higher protein yields, and improved purification and analysis of endogenous interacting protein partners.

The InterPlay adenoviral TAP System combines our unique tandem affinity purification (TAP) system with our exclusive adenoviral gene delivery system, the AdEasy Adenoviral Vector System for enhanced gene delivery to a broader range of mammalian cells, higher protein yields, and improved purification and analysis of endogenous interacting protein partners.

Agilent’s proprietary Stabilization and Drying Solution is optimized to reduce degradation of cyanine 3 and 5 by ozone during microarray processing in preparation for scanning. 

The LacSwitch II inducible mammalian expression system utilizes an improved vector system in which several elements of the lac operon have been modified for use in eukaryotic cells for the control of gene expression. The establishment of a highly regulated expression system in eukaryotic cells is an invaluable tool for the study of cell cycle, oncogenicity, cytogenicity, and the mechanisms of gene regulation.

G418 blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells. G418 Sulfate is available as a crystalline solid or in aqueous sterile solution.