Drug discovery > Target Discovery Products & Reviews

Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.

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RNace-It Ribonuclease Cocktail

Agilent Technologies

RNace-it ribonuclease cocktail is a mixture of two RNases: RNase A and a nonspecific RNase from Aspergillus oryzae. The combined action of these ribonucleases results in the degradation of RNA into small oligoribonucleotides.  Mixture of RNase A and RNase T1  Combined action of these RNases degrades RNA into small oligoribonucleotides  Tested to be free of contaminating DNase activity

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Calmodulin Affinity Resin

Agilent Technologies

The Affinity protein expression and purification system provides a simple, gentle, and effective method for high-level protein expression and purification. A complete Affinity protein expression and purification system includes calmodulin (calcium-modulated protein or CaM) affinity resin and pCAL expression vectors, containing a calmodulin-binding peptide (CBP) tag.

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Mouse CpG Island Microarray, 2x105K

Agilent Technologies

Agilent’s mouse CpG microarrays enable a comprehensive insight into the DNA methylation changes that may be correlated to key biological processes. Such processes include cancer, development, genomic imprinting, gene silencing, and chromatin stability.

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Klenow Fill-In Kit

Agilent Technologies

Choose the Klenow Fill-In Kit to perform both partial fill-in reactions to prepare genomic DNA for insertion into the Lambda FIX II vector, and complete fill-in of a 5 overhang to generate blunt ends, to allow direct ligation. Or, use the kit to radioactively end label a 5 overhang with [alpha- 32 P]dNTP.

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Luciferase Assay Kit

Agilent Technologies

The Luciferase Assay Kit provides rapid, sensitive, and quantitative measurement of American firefly (Photinus pyralis) luciferase activity in cultured mammalian cells.  Sensitive, widely used reporter assay  Rapid, quantitative results  Reporter activity immediately available upon translation  Useful in conjunction with PathDetect systems

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Mammalian Two-Hybrid Assay Kit

Agilent Technologies

The Mammalian Two-Hybrid Assay Kit is a powerful method for detecting protein-protein interactions in vivo in mammalian cells. The two-hybrid assay kit utilizes hybrid genes to detect protein-protein interactions via the activation of reporter-gene expression.  Detects protein-protein interactions in mammalian cells  Works well in a variety of mammalian cell lines  Confirms suspected interactions between two proteins or i…

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Deoxynucleotide Mix, PCR-Grade

Agilent Technologies

The PCR grade deoxynucleotide mix includes 25 mM of each standard dNTP (GATC) for use with any PCR application, including real-time quantitative PCR. These reactions buffers contain the optimal magnesium concentration for efficient PCR.

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Universal miRNA Reference Kit

Agilent Technologies

The Universal Human miRNA Reference RNA is an ideal reference control for miRNA microarray or miRNA-targeted QRTPCR experiments. The Agilent miRNA Kit may also be used as an optimization or standardization reagent for human miRNA analysis. Available in industrial lots for high throughout applications.

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Mouse miRNA Microarray Kit (V2) Kit, 8x15K

Agilent Technologies

Agilent Mouse microRNA Microarrays generate complete microRNA profiles for broad insight into mouse expression and regulation. Probe design, coupled with a unique labeling method, works in concert to provide the optimal sensitivity and specificity that your work demands.  Content regularly updated from the Sanger miRBase 16.0  Mouse and mouse viral miRNAs represented  Optimal sensitivity and specificity through unique pro…

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Mouse miRNA Microarray Kit Release 16.0, 8x60K

Agilent Technologies

Agilent Mouse microRNA Microarrays generate complete microRNA profiles for broad insight into mouse expression and regulation. Probe design, coupled with a unique labeling method, works in concert to provide the optimal sensitivity and specificity that your work demands.  Content regularly updated from the Sanger miRBase 16.0  Mouse and mouse viral miRNAs represented  Optimal sensitivity and specificity through unique pro…

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