Products & Reviews

Tumor associated macrophages (TAMs) play a key role in regulating the inflammatory or immunosuppressive state of the tumor microenvironemnt (TME). Distinguish between M1 (pro-inflammatory) and M2 (anti-inflammatory) TAMs using the PhenoCode™ Signature M1/M2 Polarization panel (CD8, CD68, CD163, PD-1, PD-L1) to evaluate polarization profiles in the TME. Map additional phenotypes by adding a 6th marker to the panel from the anti…

As the major population of immune cells within the tumor microenvironment (TME), T cells are a driver of anti-tumor immunity. T cell exhaustion and the presence of immunosuppressive cells can contribute to an immunosuppressive TME. PhenoCode™ Signature T Cell Status Panel (CD8, CD4, CD20, FoxP3, PD-1) allows for identification of distinct T Cell subsets and effector functionality status. Map additional phenotypes by adding a 6…