Drug discovery > Basic Research Products & Reviews

* Perfuse cells right in your 35mm Nunc Petri Dish (our default size)Cells cultured in Petri dishes are a popular research tool used in numerous applications, including patch clamping and intracellular ion probe imaging. True perfusion (continuous inflow and outflow) of solutions can be difficult to configure. This forces scientists to plate cells on cover slips for placement into specially designed perfusion chambers. However…

The BSC1 chamber design is similar to the original "Oslo chamber" (Langmoen & Andersen 1981) with later modifications (Dhanjal & Sears 1980, Alger et al, 1984) to allow both interface and submerged methods of slice maintenance.* "Submerged" and "Interface" methods of slice maintenance with same chamber This chamber allows adaptation to either method of slice maintenance simply by altering the fluid level by means of a screw ad…

* "Interface" method of slice maintenance* Dual feed channels for perfusion solution* Use entire surface for multiple slices or templates* Single and dual well templates, other designs available upon request* Single well template has provision for temperature probe and ground wire* Proportional temperature controller (PTC03) with low noise performance used for heating - available separatelyThis slice recording chamber is desig…

This item is the HOLDER (BSKH) and Brain Slice Keeper (S-BSK). * Slices maintained for many hours prior to transfer to recording chamber* Simple to set up and maintain * Slices supported on a quick-change nylon net The Brain Slice Keeper has been designed to pre-incubate brain slices prior to transfer into recording chambers. It consists of a pair of closely fitting acrylic rings, upper and lower, between which is wedged a she…

The MS1 chamber has been designed for use with fixed-stage upright-type microscopes. The particular feature of this chamber is the profiled contour that allows the microscope objective to sweep across the preparation when changing magnification, without having to adjust the focusing. In this way the specimen and any pre-positioned microelectrodes remain par-focal. This is particularly useful for confocal microscopy where it is…

Dovetail slide for easy removal. Manual micromanipulator with 10mm travel in all 4 axes. 5µm resolution. Ideal for stimulator applications.

Ball Bearing Manipulator with 38mm coarse and 5mm travel in the X-axis. 5µm resolution. Ideal for applications requiring multiple manipulators in one quadrant.Overall footprint dimensions: 5.33 x 2.36"

Ball Bearing Manipulator with lead screw design. Rotatable mounting base and probe holder. 22mm travel in the X-axis. 10µm resolution. Ideal for axial cell probing.

Smooth motion and instant response to hand adjustments makes theMX630 and the MX610 ideal for long term intracellular recordings. Thewater based hydraulic mechanism has a thermal expansion two to three times less than that of oil based systems, thus minimizing drift to less than 2 µm per hour at constant temperatures.MX600 series hydraulic micromanipulators have crossed roller bearings in each axis. This along with a metal bel…

The PC series perfusion chambers have embedded magnets that are conveniently located to retain perfusion plumbing and ground plugs. They are designed to fit into our 8090c fixed stage platform. A standard 22 mm cover slip is used to create the chamber bottom that is attached with vacuum grease, silicon, or parafilm (use a heat gun to gently melt the parafilm). There are two plastic retention screws for added security. Both ope…