Products, services, reviews and techniques used in lead molecule delivery, formulation and toxicology, using assays and animal models.
Cell Line Description: The ToxReporter Hmox1 Cell Line contains a reporter gene under transcriptional control of the Hemoxygenase Response Element (Hmox1) promoter. This reporter construct is stably integrated into the CHO cell line. The induction of a toxic response through the Hmox1 pathway results in the secretion of a reporter (ToxReporter) protein into the cell culture media. The secreted ToxReporter protein in the media…
ToxReporter Cell Line Starter Pack 9 is required for use with the Hmox1 ToxReporter Cell Line (Catalog # ECL-009). In response to toxic compounds, ToxReporter proteins are secreted from cells into culture media. This secreted protein may be measured using the ToxReporter ELISA kit (Catalog # ETR-201K).
The ToxReporter Cell Line Starter Pack 2 (Catalog # ECLSP-002) includes ToxReporter AP-1 Stimulant (Catalog # ESTM-002), Selection Agent (Catalog # ESA-001), and Assay Media Supplement (Catalog # EAMS-001). Each component is sufficient for 100 assay points. If needed, each individual component may be purchased separately.
The ToxReporter Cell Line Starter Pack 5 (Catalog # ECLSP-005) includes ToxReporter NFĸB Stimulant (Catalog # ESTM-005), Selection Agent (Catalog # ESA-001), and Assay Media Supplement (Catalog # EAMS-001). Each component is sufficient for 100 assay points. If needed, each individual component may be purchased separately.
The ToxReporter Cell Line Starter Pack 3 (Catalog # ECLSP-003) includes ToxReporter GRE Stimulant (Catalog # ESTM-003), Selection Agent (Catalog # ESA-001), and Assay Media Supplement (Catalog # EAMS-001). Each component is sufficient for 100 assay points. If needed, each individual component may be purchased separately. ToxReporter™ GRE Cell Line Starter Pack is required for use with the GRE ToxReporter Cell Line (Catalog #…
The ToxReporter Cell Line Starter Pack 1 (Catalog # ECLSP-001) includes ToxReporter p21 Stimulant (Catalog # ESTM-001), Selection Agent (Catalog # ESA-001), and Assay Media Supplement (Catalog # EAMS-001). Each component is sufficient for 100 assay points. If needed, each individual component may be purchased separately. ToxReporter™ p21 Cell Line Starter Pack is required for use with the p21 ToxReporter Cell Line (Catalog #…
The ToxReporter Cell Line Starter Pack 4 (Catalog # ECLSP-004) includes ToxReporter HSP70 Stimulant (Catalog # ESTM-004), Selection Agent (Catalog # ESA-001), and Assay Media Supplement (Catalog # EAMS-001). Each component is sufficient for 100 assay points. If needed, each individual component may be purchased separately. ToxReporter™ HSP70 Cell Line Starter Pack is required for use with the HSP70 ToxReporter Cell Line (Cat…
The ToxReporter Cell Line Starter Pack 8 (Catalog # ECLSP-008) includes ToxReporter ARE Stimulant (Catalog # ESTM-008), Selection Agent (Catalog # ESA-001), and Assay Media Supplement (Catalog # EAMS-001). Each component is sufficient for 100 assay points. If needed, each individual component may be purchased separately. ToxReporter Cell Line Starter Pack 8 is required for use with the ARE ToxReporter Cell Line (Catalog # EC…
One vial of ToxReporter XRE Stimulant (Catalog # ESTM-007) contains 100 µL of 100 µM 3-methylchoranthrene in 10% DMSO at 100X concentration. One vial of ToxReporter Selection Agent (Catalog # ESA-001) contains 20 mL of proprietary selection compound at 100X concentration. One vial of Assay Media Supplement (Catalog # EAMS-001) contains 1 mL of proprietary reagent at 100X concentration. ToxReporter Cell Line Starter Pack 7 is…
The ToxReporter Cell Line Starter Pack 6 (Catalog # ECLSP-006) includes ToxReporter HRE Stimulant (Catalog # ESTM-006), Selection Agent (Catalog # ESA-001), and Assay Media Supplement (Catalog # EAMS-001). Each component is sufficient for 100 assay points. If needed, each individual component may be purchased separately. ToxReporter Cell Line Starter Pack 6 is required for use with the HRE ToxReporter Cell Line (Catalog # E…
