Drug discovery > Pre-Clinical Development Products & Reviews

Products, services, reviews and techniques used in lead molecule delivery, formulation and toxicology, using assays and animal models.

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Supelco® Smart SPME Fibers

Merck

Our Smart SPME fibers are equipped with a unique Smart chip that offers traceability, ease-of-use, and increased productivity. The smart SPME fibers are an extension of our expertise and innovation from traditional SPME coatings to smart SPME format for accurate, reliable, and consistent results.

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Supelco® Overcoated (OC) SPME Fibers

Merck

The over coating of fibers is a new technology in fiber coating to protect the SPME fiber from matrix components. This allows for immersion of the fiber directly into complex samples ensuring a more efficient extraction (e.g. of semivolatile compounds). Polydimethylsiloxane (PDMS) is used to overcoat a PDMS/divinylbenzene (DVB) fiber. The resulting fiber is more physically robust and resistant to chemical fouling and allows f…

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Supelco® Nitinol Core SPME Fibers

Merck

The nitinol-core of SPME fibers enhances the fiber performance and the precision of chromatographic results to enhance lot-to-lot and fiber-to-fiber reproducibility, increase fiber durability, and maintain selectivity and inertness compared to fused silica core fibers.

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Steripak™ Filter Units

Merck

Steripak-GP filter units are designed for larger scale pressure-driven filtration of tissue culture media with or without serum. They are single use and are not autoclavable. The filter units come in two sizes, with the smaller unit able to filter up to 10 L and the larger up to 20 L. Both sizes utilize the low protein binding, fast flow 0.22 µm EMD Millipore Express membrane. Each unit has an integral filling bell for bottle-…

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Steritop™ Filter Units

Merck

Steritop bottle top filter units provide a large filter area for rapid sterile filtration of aqueous fluids into narrow-mouth (33 mm) or wide-mouth (45 mm) bottles. A small tab inside the funnel secures an optional prefilter in-place during filtration. For added protection against contamination, the threads for bottle attachment have been slightly recessed in case the funnel accidentally touches a work surface

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