Drug discovery > Target Discovery Products & Reviews

Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.

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TRAPeze® XL Telomerase Detection Kit

Merck

The TRAPEZE® XL Kit is a highly sensitive in vitro assay for the fluorometric detection of telomerase activity. As in the original TRAPEZE® Kit, primer sequence modifications that reduce amplification artifacts and an internal PCR control are included. In addition, the TRAPEZE® XL Kit uses fluorescence energy transfer (ET) primers to generate fluorescently labeled TRAP products which permit nonisotopic, quantitative analysis o…

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Amplifluor® UniPrimer II Fluorescein

Merck

The Amplifluor™ UniPrimer™-fluorescein is a hairpin primer labeled with a fluorescent energy transfer pair (fluorescein and non-fluorescent quencher) and a 3' single-stranded oligonucleotide tail and is provided at a concentration of 5.0 μM (25.0 mL).

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Sure Blot® CHEMI™ Hybridization & Detection Kit

Merck

CHEMICON's Sure Blot® CHEMI™ Hybridization & Detection Kit is designed to provide high quality, non-radioactive detection of digoxigenin-labeled DNA probes hybridized to Sure Blot® Nylon Membrane. As an integrated hybridization and detection system, Sure Blot® CHEMI™ is quality controlled to produce high signal and low background. Comparable sensitivity to 32P is typically observed for single-copy gene detection. Sufficient re…

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Rho Assay Reagent (Rhotekin RBD, agarose)

Merck

GST-tagged fusion protein, corresponding to residues 7-89 of mouse Rhotekin Rho Binding Domain, expressed in E.coli and bound to glutathione-agarose. Specifically binds to and precipitates GTP-Rho, but not GDP-Rho from cell lysates.

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