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Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.

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Stem Cell Factor, recombinant human

Merck

Stem Cell Factor (SCF) is a hematopoietic growth factor that exerts its activity at the early stages of hematopoiesis. SCF stimulates the proliferation of myeloid, erythroid, and lymphoid progenitors in bone marrow cultures and has been shown to act synergistically with colony stimulating factors. Recombinant human SCF is an 18.4 kDa protein containing 165 amino acid residues corresponding to the soluble secreted form of SCF.

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Macrophage-Colony Stimulating Factor, recombinant human

Merck

M-CSF is a potent hematopoietic factor produced by a variety of cells including lymphocytes, monocytes, fibroblasts, endothelial cells, myoblasts and osteoblasts. It is involved in development, differentiation, and survival of blood monocytes, tissue macrophages and their progenitor cells. The human is reactive in murine systems, but the murine molecule exhibits no activity on human cells.

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Vascular Endothelial Growth Factor 165, recombinant mouse

Merck

Vascular Endothelial Cell Growth Factor (VEGF) is a homodimeric protein secreted by a variety of vascularized tissues. The reported activities of VEGF include stimulation of endothelial cell growth, angiogenesis, and capillary permeability. Chemicon's mouse VEGF is a 39 kDa homodimeric protein consisting of two 165 amino acid polypeptide chains comprising the full length mouse VEGF164 sequence and an N-terminal methionine resi…

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Vascular Endothelial Growth Factor, recombinant human, 165aa isoform

Merck

Vascular Endothelial Cell Growth Factor (VEGF) is a secreted homodimeric protein secreted by a variety of vascularized tissues. The reported activities of VEGF include stimulation of endothelial cell growth, angiogenesis, and capillary permeability. Human VEGF is a 38.2 kDa homodimeric protein consisting of two 165 amino acid polypeptide chains.

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Fibroblast Growth Factor-8, recombinant human

Merck

Fibroblast Growth Factor-8 (FGF-8) is a heparin binding growth factor that stimulates the proliferation and activation of cells that express FGF receptors. Recombinant Human FGF-8 is a 22.4 kDa protein containing 193 amino residues.

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BAFF, recombinant human

Merck

Human BAFF (B-cell activating factor belonging to the TNF family) is a novel ligand in the TNF family. BAFF plays an important role as co-stimulator of B-cell proliferation and function. Recombinant human BAFF is a soluble 17.0 kDa protein containing 153 amino acid residues, comprising the TNF-like extracellular domain of BAFF.

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Epidermal Growth Factor, recombinant mouse

Merck

Epidermal Growth Factor (EGF) is a polypeptide growth factor, which stimulates the proliferation of a wide range of epidermal and epithelial cells. Recombinant murine EGF is a 6.2 kDa protein containing 54 amino acid residues.

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Glucagon RIA

Merck

Glucagon is a 3,5 kDa hormone secreted by the A cells of the Islets of Langerhans in the pancreas and is involved in regulation of glucose homeostasis thro µgh enhanced synthesis and mobilization of glucose in the liver, and regulation of glucose-stimulated insulin secretion.

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