Drug discovery > Target Discovery Products & Reviews

Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.

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Chromatin Immunoprecipitation (ChIP) Assay Kit

Merck

For use to enrich for specific regions of chromatin that are immunoprecipitated with a specific antibody for a chromatin protein. Works with all eukaryotic cell types. Detection of the gene or promoter of interest in immunoprecipitated chromatin must be empirically determined by the researcher. Quantitative PCR detection is recommended.

4.0/5.0
|1 Review

Caspase 3/7 Reagent Kit (100 tests)

Merck

The Guava® Caspase 3/7 and 8 Assays employ a FLICA (Fluorescent Labeled Inhibitor of Caspases) reagent that specifically identifies active caspase 3 and 7 molecules or caspase 8 molecules. Non-cytotoxic, cell permeant dyes elimiate lysis and permeabilization procedures. Each FLICA is comprised of three subunits: A caspase-specific amino acid inhibitor containing a recognition sequence for caspase 3/7 (DEVD) or caspase 8 (LETD)…

3.9/5.0
|2 Reviews

SNAP i.d. 2.0 System

Merck

The SNAP i.d. Protein Detection System revolutionizes the quality of your blots every time — in record time! Unlike conventional Western blotting, where diffusion is the primary means of reagent transport, the SNAP i.d. system applies a vacuum to actively drive reagents through the membrane. This novel method allows you to optimize your blotting conditions in record time for maximum results. The SNAP i.d. system minimizes over…

4.4/5.0
|14 Reviews

Image Stream®X Mark II Imaging Flow Cytometer

Merck

The revolutionary ImageStream®X Mark II Imaging Flow Cytometer combines the speed, sensitivity, and phenotyping abilities of flow cytometry with the detailed imagery and functional insights of microscopy. This unique combination enables a broad range of applications that would be impossible using either technique alone. This instrument produces multiple high-resolution images of every cell directly in flow, including brightfie…

4.3/5.0
|1 Review

QCM Chemotaxis Cell Migration Assays

Merck

Chemotaxis assays are ideal for assessing the effects of pharmacological compounds on the motility of tumor cells, and for analyzing the migratory capacity of multiple cell lines in parallel. The format options enable large-scale screening and quantitative comparison of multiple samples in a user friendly, sensitive, HTS system. Quantitative fluorescent method increases sensitivity 10-fold over similar assays on the market…

4.0/5.0
|1 Review

Samplicity® filtration system

Merck

Introducing a vacuum filtration system that makes sample preparation easy: the EMD Millipore Samplicity filtration system with Millex Samplicity membrane filters. With the Samplicity® filtration system and Millex Samplicity® membrane filters, EMD Millipore has transformed sample preparation forever. Advantages of the EMD Millipore Samplicity filtration system include:   •  Higher throughput with simultaneous vacuum filtration…

4.3/5.0
|1 Review

Mouse Leptin ELISA

Merck

Leptin is synthesized in adipocytes as a 16 kDa molecule and the circulating level is directly proportional to the total amount of fat in the body.

3.3/5.0
|1 Review


m-FC Agar

Merck

Membrane Filter Fecal Coliform Agar. Typical Composition (g/L): Proteose peptone 5.0; bile salts 1.5; tryptose 10.0; lactose 12.5; yeast extract 3.0; methyl-blue (formerly aniline blue) 0.1; sodium chloride 5.0; agar-agar 15.0.Application: For the detection of fecal coliforms in water using the membrane filter technique.

2.7/5.0
|1 Review

High-Definition Erenna® Immunoassay System

Merck

The Erenna Immunoassay System, powered by Singulex's patented single-molecule detection technology, accelerates biomedical and translational research by accurately and reliably quantifying low-abundance biomarkers at or below sub-picogram concentrations. This unique high-definition technology enables distinct stratification of healthy and disease subjects through a broad dynamic range of over 4 logs, enhancing the clinical uti…

1.7/5.0
|1 Review