A cell-permeable (thienothienyl)amino-acetamide compound that displays anti-inflammatory properties. Acts as a potent, reversible, ATP-competitive, and highly selective inhibitor of IKK-2 (IC50 ~3-12 µM for IKK-2 homodimer, IKK-1/IKK-2 heterodimer, and IKK-2). Its specificity has been confirmed using a panel of 31 other kinases, including IKK isoforms IKK-1, IKK-i, and TBK-1 (IC50 > 200 µM). Shown to specifically block NF-kB-d…
New Release 2009! 3D Prime Culture Medium. Improving still further our originial medium for 3D culture of epidermal keratinocytes, CELLnTEC has now released a new formulation, known as 3D Prime.Developed using our established signalling-based approach, this completely defined medium enables more rapid establishment of a fully stratified epidermis. Using this medium, models can now be ready for experimentation in just 14-18 day…
CnT-27 is a progenitor cell targeted (PCT) liquid culture medium kit including both basal medium and separate supplements, developed for improved isolation and growth of mammary epithelium. CnT-27 is fully defined, serum and BPE-free formulation. It does not contain antibiotics / antimycotics. The basal medium contains amino acids, minerals, vitamins and organic compounds, but is protein free.
ESGRO Complete PLUS Clonal Grade Medium is a defined serum-free medium provided with a selective GSK3β inhibitor to enhance viability of mouse embryonic stem (ES) cells and increased maintenance of pluripotency in the absence of serum and feeder cells. This medium is intended for mouse ES cell expansion and growth at clonal density in serum-free conditions. The mouse ES cells should maintain germ line competency. Suitable fo…
Cell Line Description: The ToxReporter ARE Cell Line contains a reporter gene under transcriptional control of the Antioxidant Response Element (ARE) promoter. This reporter construct is stably integrated into the MCF-7 cell line. The induction of a toxic response through the ARE pathway results in the secretion of a reporter (ToxReporter) protein into the cell culture media. The secreted ToxReporter protein in the media can t…
Cell Line Description: The ToxReporter XRE Cell Line contains a reporter gene under transcriptional control of the Xenobiotic Response Element (XRE) promoter. This reporter construct is stably integrated into the MCF-7 cell line. The induction of a toxic response through the XRE pathway results in the secretion of a reporter (ToxReporter) protein into the cell culture media. The secreted ToxReporter protein in the media can th…
Cell Line Description: The ToxReporter HRE Cell Line contains a reporter gene under transcriptional control of the Hypoxia Response Element (HRE) promoter. This reporter construct is stably integrated into the MCF-7 cell line. The induction of a toxic response through the HRE pathway results in the secretion of a reporter (ToxReporter) protein into the cell culture media. The secreted ToxReporter protein in the media can then…
Cell Line Description: The ToxReporter Hmox1 Cell Line contains a reporter gene under transcriptional control of the Hemoxygenase Response Element (Hmox1) promoter. This reporter construct is stably integrated into the CHO cell line. The induction of a toxic response through the Hmox1 pathway results in the secretion of a reporter (ToxReporter) protein into the cell culture media. The secreted ToxReporter protein in the media…
ToxReporter Cell Line Starter Pack 9 is required for use with the Hmox1 ToxReporter Cell Line (Catalog # ECL-009). In response to toxic compounds, ToxReporter proteins are secreted from cells into culture media. This secreted protein may be measured using the ToxReporter ELISA kit (Catalog # ETR-201K).
The ToxReporter Cell Line Starter Pack 2 (Catalog # ECLSP-002) includes ToxReporter AP-1 Stimulant (Catalog # ESTM-002), Selection Agent (Catalog # ESA-001), and Assay Media Supplement (Catalog # EAMS-001). Each component is sufficient for 100 assay points. If needed, each individual component may be purchased separately.
The ToxReporter Cell Line Starter Pack 5 (Catalog # ECLSP-005) includes ToxReporter NFĸB Stimulant (Catalog # ESTM-005), Selection Agent (Catalog # ESA-001), and Assay Media Supplement (Catalog # EAMS-001). Each component is sufficient for 100 assay points. If needed, each individual component may be purchased separately.
The ToxReporter Cell Line Starter Pack 3 (Catalog # ECLSP-003) includes ToxReporter GRE Stimulant (Catalog # ESTM-003), Selection Agent (Catalog # ESA-001), and Assay Media Supplement (Catalog # EAMS-001). Each component is sufficient for 100 assay points. If needed, each individual component may be purchased separately. ToxReporter™ GRE Cell Line Starter Pack is required for use with the GRE ToxReporter Cell Line (Catalog #…
The ToxReporter Cell Line Starter Pack 1 (Catalog # ECLSP-001) includes ToxReporter p21 Stimulant (Catalog # ESTM-001), Selection Agent (Catalog # ESA-001), and Assay Media Supplement (Catalog # EAMS-001). Each component is sufficient for 100 assay points. If needed, each individual component may be purchased separately. ToxReporter™ p21 Cell Line Starter Pack is required for use with the p21 ToxReporter Cell Line (Catalog #…
The ToxReporter Cell Line Starter Pack 4 (Catalog # ECLSP-004) includes ToxReporter HSP70 Stimulant (Catalog # ESTM-004), Selection Agent (Catalog # ESA-001), and Assay Media Supplement (Catalog # EAMS-001). Each component is sufficient for 100 assay points. If needed, each individual component may be purchased separately. ToxReporter™ HSP70 Cell Line Starter Pack is required for use with the HSP70 ToxReporter Cell Line (Cat…
The ToxReporter Cell Line Starter Pack 8 (Catalog # ECLSP-008) includes ToxReporter ARE Stimulant (Catalog # ESTM-008), Selection Agent (Catalog # ESA-001), and Assay Media Supplement (Catalog # EAMS-001). Each component is sufficient for 100 assay points. If needed, each individual component may be purchased separately. ToxReporter Cell Line Starter Pack 8 is required for use with the ARE ToxReporter Cell Line (Catalog # EC…
One vial of ToxReporter XRE Stimulant (Catalog # ESTM-007) contains 100 µL of 100 µM 3-methylchoranthrene in 10% DMSO at 100X concentration. One vial of ToxReporter Selection Agent (Catalog # ESA-001) contains 20 mL of proprietary selection compound at 100X concentration. One vial of Assay Media Supplement (Catalog # EAMS-001) contains 1 mL of proprietary reagent at 100X concentration. ToxReporter Cell Line Starter Pack 7 is…
The ToxReporter Cell Line Starter Pack 6 (Catalog # ECLSP-006) includes ToxReporter HRE Stimulant (Catalog # ESTM-006), Selection Agent (Catalog # ESA-001), and Assay Media Supplement (Catalog # EAMS-001). Each component is sufficient for 100 assay points. If needed, each individual component may be purchased separately. ToxReporter Cell Line Starter Pack 6 is required for use with the HRE ToxReporter Cell Line (Catalog # E…
This ToxReporter Cell Line is used in conjunction with the ToxReporter ELISA kit (cat# ETR-201K) for the measurement of ToxReporter protein secreted into cell culture media as a consequence of exposure to a potential toxin. The cell line has been designed to respond to stimuli that induce cellular stress response pathways. Examples of stressful stimuli include compounds in drug discovery and organic or inorganic molecules pote…
This ToxReporter Cell Line is used in conjunction with the ToxReporter ELISA kit (cat# ETR-201K) for the measurement of ToxReporter protein secreted into cell culture media as a consequence of exposure to a potential toxin. The cell line has been designed to respond to stimuli that induce cellular stress response pathways. Examples of stressful stimuli include compounds in drug discovery and organic or inorganic molecules pote…
This ToxReporter Cell Line is used in conjunction with the ToxReporter ELISA kit (cat# ETR-201K) for the measurement of ToxReporter protein secreted into cell culture media as a consequence of exposure to a potential toxin. The cell line has been designed to respond to stimuli that induce cellular stress response pathways. Examples of stressful stimuli include compounds in drug discovery and organic or inorganic molecules pote…
This ToxReporter Cell Line is used in conjunction with the ToxReporter ELISA kit (cat# ETR-201K) for the measurement of ToxReporter protein secreted into cell culture media as a consequence of exposure to a potential toxin. The cell line has been designed to respond to stimuli that induce cellular stress response pathways. Examples of stressful stimuli include compounds in drug discovery and organic or inorganic molecules pote…
This ToxReporter Cell Line is used in conjunction with the ToxReporter ELISA kit (cat# ETR-201K) for the measurement of ToxReporter protein secreted into cell culture media as a consequence of exposure to a potential toxin. The cell line has been designed to respond to stimuli that induce cellular stress response pathways. Examples of stressful stimuli include compounds in drug discovery and organic or inorganic molecules pote…
This kit is used for the non-radioactive quantification of ToxReporter protein that is secreted into cell culture media. One kit is sufficient to measure 38 unknown samples in duplicate.
High Content Analysis (HCA) is rapid, automated microscopy providing quantitative image acquisition and analysis. Using Millipore’s superior-quality reagents in ready-to-use kits and cell-based assays that incorporate the power of HCA, researchers around the world are able to learn more about relevant functional cell biology in many different systems, including assessment of DNA damage and apoptosis. Millipore’s HCA kits inclu…
For simple, cost-effective protein detection, use Millipore's Western blotting reagents to achieve the highest sensitivity with the least background. Bløk™ Noise Cancelling Reagents Bløk reagents minimize background in Western blots, increasing sensitivity for superior detection of even low-abundance proteins. Bløk reagents are protein-free, which reduces non-specific binding, especially when you are using phosphoantibodies o…
