Identification and optimization of the chemical, series of chemicals or bio-molecule that will interact with the target using impartial, expert opinion about the best equipment, services and the latest techniques
The OPTI-SOLV® Mini Filter provides low-impact filtration in a package no larger than a finger tight fitting. Use them to extend the life of your analytical column, or before your mass spectrometer as a last line of defense against debris. Perfect zero-dead-volume connections are obtained every time with our patented automatic tube stop depth adjustment. Unique depth-filtering elements allow for greater capacity with no band s…
The OPTI-SOLV® Nano Filter follows our Micro Filter but cuts the internal volume down even further. With less than 50 nL of internal volume, the OPTI-SOLV® Nano Filter is ideal for mass spectrometry to protect your electrospray and nanospray tips from clogging with debris. Like the Micro and Mini Filter, the Nano Filter is designed to be used in today's low volume, high sensitivity chromatographic applications as a last line o…
For your volume critical filtering needs, we now offer the OPTI-SOLV® Micro Filter. Based on the same design that has made the Mini Filter a huge success, the Micro Filter cuts the internal volume to less than 200 nL but retains the ease of use and functionality of the Mini Filter. The Micro Filter is designed to be used in today's low volume, high sensitivity chromatographic applications as a last line of defense against debr…
The user-friendly Hand-Tight OPTI-SOLV® In-Line Filter System is well suited for a number of applications, such as high temperature, high-pressure environments where quick changes are imperative. The unique swivel design allows frits to be changed without removing the connecting tubing. Just plumb it once and leave it. The frictional forces generated at the piston/seal interface inevitably lead to particulate shedding. Placeme…
The user-friendly Wrench-Tight OPTI-SOLV® In-Line Filter System is well suited for a number of applications, such as high temperature, high-pressure environments where quick changes are imperative. The unique swivel design allows frits to be changed without removing the connecting tubing. Just plumb it once and leave it. The frictional forces generated at the piston/seal interface inevitably lead to particulate shedding. Place…
OPTI-GUARD® 1mm Biocompatible Guard Columns set the standard for extremely low impact, easy to use pre-column protection. Designed for use with analytical (4.6, 3.0 mm i.d.) and narrow-bore (2.1, 1.0 mm i.d.) columns, the patented floating stem design automatically adjusts to any manufacturer's tube stop depth for a zero-dead-volume connection every time. The best part? It's no larger than a standard fitting. Connecting the OP…
The OPTI-GUARD® 3 mm Columns maintains the tool-free connectivity of the OPTI-GUARD 1 mm, but incorporates a cartridge based format to allow for a larger bed with more capacity. The two-part holder is designed for use with any analytical column to provide vital protection from dirty samples and strongly retained contaminants. An auto-adjusting stem conforms to any tube stop depth for a perfect zero-dead-volume connections.Key…
OPTI-SEAL® Piston/Plunger Seals are the longest lasting seals on the market. Machined from either of two proprietary polymer blends, UHMW-PE or ITB, Optimize Seals provide the ultimate in high pressure sealing capacity. For mostly aqueous buffered mobile phases, OPTI-SEAL® UHMW-polyethylene is the wisest choice. Specially designed to be more resistant to abrasion and wear than standard polyethylene seals, they can last up to s…
Optimize realizes that your time is valuable and should not be wasted worrying about fittings. For this reason, all Opti-Lock Fittings are precision machined in the USA for optimal quality and thread consistency. The machining process is the best way to ensure tight manufacturing tolerances and minimal product variance. What does all this mean? It means that every fitting you purchase from Optimize will perform just as well as…
Optimize Back Pressure Regulators utilize an active mechanism to maintain steady back pressure across a range of mobile phase viscosities and flow rates. Placing one downstream from your detector will prevent solvent decompression and bubble formation in the flow cell, reducing baseline noise and drift. Each pre-set Optimize stainless steel Back Pressure Regulator offers a 100µL internal volume and includes fittings for immedi…
